imagen animada PEDECIBA
Investigadores :

Página personal de la Dra. Beatriz María Alvarez Sanna


http://www.rau.edu.uy/pedeciba/personas/alvarezs.htm

La Dra. Beatriz Alvarez es investigadora Grado 4 en el Area Química del PEDECIBA habiendo sido designada en 2001 e investigadora Grado 3 en el Area de Biología desde 2003. Desempeña sus actividades en el Laboratorio de Enzimología, Facultad de Ciencias.

Línea de investigación:

  • Bioquímica de radicales libres.

    Dirección postal:
    Laboratorio de Enzimología,
    Instituto de Química Biológica
    Facultad de Ciencias
    Universidad de la República
    Iguá 4225
    Montevideo 11400
    Uruguay
    tel: (+598 2) 525 8618-23 int. 214
    fax: (+598 2) 525 8617
    e-mail: beatriz.alvarez@fcien.edu.uy



  • Publicaciones


    • Carballal S, Radi R, Kirk MC, Barnes S, Freeman BA, Alvarez B
      Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite
      Biochemistry, 42: 9906-9914 (2003)

    • Naya H, Romero H, Zavala A, Alvarez B, Musto H
      Aerobiosis increases the genomic guanine plus cytosine content (GC%) in prokaryotes
      J Mol Evol, 55(3): 260-264 (2002)

    • Alvarez B, Radi R
      Peroxynitrite reactivity with amino acids and proteins
      Amino Acids (2002) (en prensa)

    • Ferrer-Sueta G, Quijano C, Alvarez B, Radi R
      Reactions of manganese porphyrins and Mn superoxide dismutase with peroxynitrite
      Method Enzymol, 349: 23-37 (2002)

    • Blanchard-Fillion B, Souza JM, Friel T, Jiang GC, Vrana K, Sharov V, Barron L, Schoneich C, Quijano C, Alvarez B, Radi R, Przedborski S, Fernando GS, Horwitz J, Ischiropoulos H
      Nitration and inactivation of tyrosine hydroxylase by peroxynitrite
      J Biol Chem, 276(49), 46017-46023 (2001)

    • Alvarez B, Radi R
      Peroxynitrite decay in the presence of hydrogen peroxide, mannitol and ethanol: a reappraisal
      Free Radic Res, 34(5): 467-75 (2001)

    • Schöpfer F, Riobó N, Carreras MC, Alvarez B, Radi R, Boveris A, Cadenas E, Poderoso, JJ
      Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage. The reaction between quinol and peroxynitrite: mitochondrial protective relevance
      Biochem J, 349(1): 35-42 (2000)

    • Radi R, Denicola A, Alvarez B, Ferrer-Sueta G, Rubbo H
      The Biological Chemistry of Peroxynitrite
      In: Nitric Oxide: Biology and Pathobiology, Ignarro, L. J. (Ed.) Academic Press, pp. 57-82 (2000)

    • Alvarez B, Ferrer-Sueta G, Freeman BA, Radi R
      Kinetics of peroxynitrite reaction with amino acids and human serum albumin as a model protein
      J Biol Chem, 274(2): 842-848 (1999)

    • Gatti RM, Alvarez B, Vasquez-Vivar J, Radi R, Augusto O
      Formation of spin trap adducts during the decomposition of peroxynitrite
      Arch Biochem Biophys, 349: 36-46 (1998)

    • Alvarez B, Ferrer-Sueta, G, Radi, R
      Slowing of peroxynitrite decomposition in the presence of mannitol and ethanol
      Free Radic Biol Med, 24 (7-8): 1331-1337 (1998)

    • Quijano C, Alvarez B, Gatti RM, Augusto O, Radi R
      Pathways of peroxynitrite oxidation of sulfhydrils
      Biochem J, 322: 167-173 (1997)

    • Alvarez B, Rubbo H, Kirk M, Barnes S, Freeman BA, Radi R
      Peroxynitrite-dependent tryptophan nitration
      Chem Res Toxicol, 9(2): 390-396 (1996)

    • Ureta A, Alvarez B, Ramón A, Vera MA, Martínez-Drets G
      Identification of Acetobacter diazotrophicus, Herbaspirillum seropedicae and Herbaspirillum rubrisubalbicans using biochemical and genetic criteria
      Plant and Soil, 172: 271-277 (1995)

    • Alvarez B, Martínez-Drets G
      Metabolic characterization of Acetobacter diazotrophicus
      Can J Microbiol, 41(10): 918-924 (1995)

    • Alvarez B, Denicola A, Radi R
      Reaction between peroxynitrite and hydrogen peroxide: formation of oxygen and slowing of peroxynitrite decomposition
      Chem Res Toxicol, 8(6): 859-869 (1995)