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Página Personal del Dr. Alvaro G. Estévez


http://www.rau.edu.uy/pedeciba/personas/estevez.htm

Curriculum electrónico basado en CvLac-Lattes para investigadores del PEDECIBA

Alvaro G. Estévez, Ph.D., es investigador Grado 4 en el Area Biología del PEDECIBA. Ingresó al Programa en 1992. Desempeña sus actividades en Birmingham, Estados Unidos.

Línea de investigación:

  • Excitotoxicidad y neurobiología del neuropéptido NAAG en cultivos primarios de neuronas
  • Dirección:
    Alvaro G. Estévez, Ph.D.
    Assistant Professor
    Department of Physiology and Biophysics
    The University of Alabama at Birmingham
    MCLM 850
    1918 University Boulevard
    Birmingham, Alabama 35294-0005
    Estados Unidos
    Tel: (1 205) 934 4271
    Fax (1 205) 975 7679
    e-mail :aestevez@burke.org
    Dirección postal:
    1530 3rd Avenue South
    Birmingham, AL35294-0005
    Estados Unidos



    Publicaciones


    • Gonzalez Solveyra, C.; Romeo, H.E.; Rosenstein, R.E.; Estévez, A.G.; Cardinali, D.P.
      Benzodiazepine binding in rat interscapular brown adipose tissue: Effect of cold environment, denervation and endocrine ablations
      Life Sci., 42: 393-402 (1988)

    • Gonzalez Solveyra, C.; Estévez, A.G.; Cardinali, D.P.
      GABA and its neural regulation in rat adipose tissue
      J. Neural. Trans., 78: 17-22 (1989)

    • Rosenstein, R.E.; Estévez, A.G.; Cardinali, D.P.
      Time-dependent effect of melatonin on glutamic acid decarboxylase activity and 36Cl-influx in rat hypothalamus
      J. Neuroend., 1:443-447 (1989)

    • Estévez A.G.; Calamante, G.; Goin M.; Jiménez de Asúa L.
      Tunicamicin inhibits the initiation of DNA synthesis stimulated by prostaglandin F2¬ in Swiss mouse 3T3 cells
      FEBS Lett., 290:239-242 (1991)

    • Bley, M.A.; Simón, J.C.; Estévez, A.G.; Jiménez de Asúa, L.; Barañao, L.
      Effect of Follicle-Stimulating Hormone on Insulin-like Growth Factor I-stimulated rat granulose cell deoxyribonucleic acid synthesis
      Endocrinology, 131: 1223-1229 (1992)

    • Estévez, A.G.; Stutzmann, J.-M.; Barbeito, L.
      Excitatory aminoacid-mediated neurotoxicity in motoneuron-enriched cultures: Protective effect of riluzole
      Eur. J. Pharmacol., 280:47-53 (1995)

    • Estévez, A.G.; Radi, R.; Barbeito, L.; Shin, J.T.; Thompson, J.A.; Beckman, J.
      Peroxynitrite-induced cytotoxicity in PC12 cells: Evidence for an apoptotic mechanism differentially modulated by trophic factors
      J. Neurochem, 65: 1543-1550 (1995)

    • Spear, N; Estévez, A.G.; Barbeito, L.; Beckman, J.S.; Johnson, G.V.W.
      Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase
      J. Neurochem., 69: 53-59 (1997)

    • Spear, N.; Estévez, A.G.; Radi, R.; Beckman, J.S.
      Peroxynitrite and cell signaling.
      In: "Oxidative Stress and Signal Transduction", H.J. Forman and E. Cadenas Eds. Chapman & Hill, New York. pp31-51 (1997)

    • Peluffo, H.; Estévez, A.G.; Barbeito, L.; Stutzmann, J.M.
      Riluzole promotes motoneuron survival by stimulating trophic activity produced by spinal astrocyte monolayres
      Neurosci. Lett., 228:207-211 (1997)

    • Estévez, A.G.; Spear, N.; Manuel, S.M.; Radi, R.; Henderson, C.E.; Barbeito, L.; Beckman, J.S.
      Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation
      J. Neurosci., 18:923-931 (1998)

    • Estévez, A. G.; Spear, N.; Thompson, J. A.; Cornwell, T. L.; Radi, R.; Barbeito, L.; Beckman, J. S.
      Nitric oxide dependent production of cGMP supports survival of rat embryonic motor neurons cultured with brain derived neurotrophic factor
      J Neurosci., 18: 3708-3714 (1998)

    • Spear, N.; Estévez, A.G.; Johnson, G.V.W.; Bredesen, D.E.; Thompson, J.A.; Beckman, J.S.
      Enhancement of peroxynitrite-induced apoptosis in PC12 cells by FGF-1 and NGF requires p21RAS activation and is suppressed by Bcl-2
      Arch. Biochem. Biophys., 356: 41-45 (1998)

    • Estévez, A.G.; Spear, N.; Manuel, S.M.; Barbeito, L.; Radi, R.; Beckman, J.S.
      Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
      Prog. Brain. Res., 118: 269-280 (1998)

    • Eiserich JP, Estévez AG, Bamberg T, Ye YZ, Beckman JS, Freeman BA
      Altered microtubule structure and function by post-translational incorporation of nitrotyrosine into a-tubulin
      Proc Natl Acad Sci USA, 96: 6365-6370(1999)

    • Estévez, A.G.; Spear, N.; Peluffo, H.; Kamaid, A.; Barbeito, L.; Beckman, J.S.
      Examining apoptosis in cultured cells after exposure to nitric oxide and peroxynitrite
      Meth. Enzymol., 301: 393-402 (1999)

    • Viera, L.; Ye, Y.; Estévez, A.G.; Beckman, J.S.
      Immunohistochemical methods to detect nitrotyrosine
      Meth. Enzymol., 301: 373-381 (1999)

    • Estévez AG, Crow JP, Sampson JB, Reiter C, Zhuang Y, Richardson GJ, Tarpey MM, Barbeito L, Beckman JS
      Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase Science, 286:2498-2500 (1999)

    • Lang JD, Chumley P, Eiserich, JP, Estévez A, Bamberg T, Adhami A, Crow J, Freeman BA
      Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway
      Am J Physiol, 279: L994-L1002 (2000)
    • .

    • Estévez AG, Sampson JB, Zhuang Y, Spear N, Richardson GJ, Crow JP, Tarpey MM, Barbeito L, Beckman JS
      Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron apoptosis induced by trophic factor withdrawal
      Free Radical Biol Med, 28(3): 437-446 (2000)

    • Beckman JS, Viera L, Estévez AG, Teng RJ
      Nitric Oxide and peroxynitrite in the perinatal period
      In: "Seminars in Perinatology" G. Chaudhuri, D. McNellis and C.Y. Spong Eds. W.B. Saunders, Philadelphia. pp. 37-41 (2000)

    • Estévez AG, Viera L, Kamaid A, Beckman JS
      Nitric oxide toxicity in neuronal injury and degeneration In: "Nitric Oxide and Free Radicals in Peripheral Neurotransmission". S. Kalsner, Ed., Springer-Verlag, New York, NY, pp. 262-278 (2000)

    • Beckman JS, Crow JP, Estévez AG
      Response to Toxicity of ALS-linked SOD1 mutants (Technical Comment)
      Science, 288: 399a-399b (2000)