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Investigadores :

Página personal de la Dra. Alba León


http://www.rau.edu.uy/pedeciba/personas/leon.htm

La Dra. Alba León es investigadora Grado 5 en el Area Química del PEDECIBA. Ingresó al Programa en 1989. Desempeña sus actividades en el Laboratorio de Radioquímica, Facultad de Química.

Línea de investigación:

  • Diseño de nuevos radiofármacos
  • Dirección postal:
    Laboratorio de Radioquímica,
    Facultad de Química
    Universidad de la República
    Av. Gral. Flores 2124
    Montevideo 11800
    Uruguay
    tel: (+598 2) 924 1908
    fax: (+598 2) 924 1906
    e-mail: aleon@fq.edu.uy



    Publicaciones


    • Savio E, Fagiolino P, Solanas G, Parente E, León A
      Development of w/o Phenytoin emulsions. Bioavailability in rats
      Science et Technique pharmaceutique: STP Pharma Sciences, 1-6: 379-385 (1991)

    • Savio E, Gambino D, León A, Kremer C, Kremer E
      Electrolytic 99mTc04 reduction: a different pathway to obtain 99mTc complexes
      Appl Radiat Isotopes, Int J Radiat Appl Instrum, Part A 42-7: 669-672 (1991)

    • León A, Fagiolino P, Savio E, Vázquez M
      Bioavailability of a Phenytoin w/o emulsion in humans (II)
      STP Pharma Sciences, 2-5: 415-419 (1992)

    • Kronauge J, Verdera S, León A, Balter H, León E, Mut F, Oliveira C, García F, Holman L, Davison A
      Human pharmacokinetics and radiopharmacological studies of the myocardial perfusion agent: Technetium(II-Carbomethaxy-2-methyl-ethylisocyanide)6, [99m-Tc-CPI]
      J Nucl Med, 33: 1949-1957 (1992)

    • Kremer C, León A, Kremer E
      Chemical reactivity of analogous technetium(V) and Rhenium(V) dioxo complexes
      J Radioan Nucl Ch Le, 176-2: 143-152 (1993)

    • Kremer C, León A, Kremer E
      Compared chemical reactivity of analogous Tc(V) and Re(V) dioxo complexes
      J Radioan Nucl Ch Le, 176-2: 143-152 (1993)

    • Balter H, Verdera S, Souto B, Oliver P, León A
      Radiopharmacological studies of 99m-Tc-CPI: experience with isolated rat atrial tissue
      Nucl Med Biol, International Journal of Radiation Applications and Instrumentation, Part B, 20-2: 127-132 (1993)

    • Savio E, Fagiolino P, Jelen M, León A
      Influence of the emulsion sign in phenytoin bioavailability
      Bollettino Chimico Farmaceutico, 133-4: 239-245 (1994)

    • Savio E, León A, Rey A, López J, Kremer E
      99mTc-ADP, a potential agent for in vivo tumor detection
      J Nucl Biol & Med (1994)

    • González S, Teran M, León A, Savio E, Nieto A
      Assessment of the diagnostic value of 99m Tc-radiolabelled specific antibodies in experimental hydatidosis
      Q J Nucl Med, 40-2: 161-169 (1996)

    • León A, Rey A, León E, Savio E, Kremer C, Nappa A, Chiozzone R, Campos E
      Labelling, control and radiopharmacological evaluation of 99mTc-ADP as tumour seeking agent
      Quartely J Nucl Med, 40(2): 170-175 (1996)

    • Rey A, Teran M, Kremer C, Molina S, Gambino D, Kremer E, León A
      Preparation of 99m Tc-thiourea complex as precursor of Tc(III) labelled compounds
      J Radioan Nucl Ch Le, (1996)

    • Torres J, González R, Kremer C, León A, Kremer E
      Kinetic study of the substitution of [Tc(tu)6]3+ by polyaminocarboxylic acids
      Radiochim Acta, 77: 235-240 (1997)

    • Verdera S, Gaudiano J, León A, Martínez G, Roble A, Savio E, León E, McPherson DW, Knapp F
      Rhenium-188-HEDP-Kit formulation and quality control
      Radiochim Acta, 219: 1-5 (1997)

    • Deicas B, Gambino D, Kremer C, Kremer E, Mombrú A, Suescun L, Mariezcurrena R, González O, Rey A, Mallo L, León A
      Synthesis, characterization and spectroscopic properties of [CuI(alkylisocyanide)4]BF4 complexes. X-ray crystal structures of [Cu(MIBI)4]BF4 and [Cu(CPI)4]BF4
      Polyhedron, 16: 2397 (1997)