imagen animada PEDECIBA
Investigadores :

Página personal del Dr. Patrick Moyna


http://www.rau.edu.uy/pedeciba/personas/moyna.htm

El Dr. Patrick Moyna es investigador Grado 5 en el Area Química del PEDECIBA. Ingresó al Programa en 1987. Desempeña sus actividades en Cátedra de Farmacognosia/Productos Naturales, Facultad de Química.

Investiga en las siguientes líneas:

  • Composición de ceras vegetales y marcado de triterpenos con isótopos estables
  • Aislamiento, purificación, semi-síntesis de productos naturales
  • Ensayos de actividad microbiana y biotransformaciones
  • Identificación de sus diferentes componentes

    Dirección postal:
    Cátedra de Farmacognosia y Productos Naturales
    Facultad de Química
    Universidad de la República
    Av. Gral. Flores 2124
    Montevideo 11800
    Uruguay
    tel: +598 2 924 2675
    fax: +598 2 924 1906
    e-mail:pmoyna@fq.edu.uy



  • Publicaciones


    • Rossini C, Dellacassa E, Martínez R, Moyna P
      Determination of Citral in citrus essential oils by TCL-densitometry
      Journal of Planar Chromatography, 4: 259-261 (1991)

    • Tietze Lutz F, Moyna P, Neunhaber H, Heinzen H, Ritsche M
      Labelling of Betulin with 2 H and 13C for biological transformations
      Liebigs Ann Chem, 1245 (1991)

    • Davyt D, Ferreira F, Moyna P, Dellacassa E, Menéndez P,
      Phytochemical screening of Uruguayan medicinal plants
      Fitoterapia, LXII-6: 519-521 (1991)

    • Dellacassa E, Menéndez P, Verzera A, Rossini C, Moyna P, Dugo G
      Citrus essential oils of Uruguay. Part I. Composition of oils of some varieties of mandarin cultivated in Uruguay
      J Essent Oil Res, 3: 265-272 (1992)

    • Dellacassa E, Moyna P
      Eucalyptus leaf oils. Use, chemistry, distillation and marketing
      Flav Fragr J, 7 (1992)

    • Ferreira F, Moyna P
      Simple TLC method for semi-quantitative separation of lipid clases in ciastal sediments
      J Liquid Chromatogr, 15: 1655-1663 (1992)

    • Heinzen H, Moyna P
      Activity of wax constituents on denatured cellular structures
      Oyton, 54: 51-58 (1993)

    • González A, Vázquez A, Ferreira F, Moyna P
      Biological screening of Uruguayan medicinal plants
      J Ethnopharmacol, 39: 217-220 (1993)

    • Pasqual M, Lauer C, Moyna P, Henriquez JAP
      Genotoxicity of the isoquinoline alkaloid berberine in prokariotic and eukariotic organisms
      Mutation Res, 286: 243-252 (1993)

    • García S, Heinzen H, Martínez R, Moyna P
      Identification of flavonoids by TCL densitometry
      Chromatographia, 35: 430-434 (1993)

    • Ferreira F, Soulé S, Moyna P, Vázquez A
      Rapid quantitative determination of Solanum glycoalcaloids by TLC-scanning
      J Chromatogr, 653: 380-384 (1993)

    • Dellacassa E, Martínez R, Moyna P
      Spectrodensitometric determination of o-phenyl phenol, imazalil and thiabendazol present as residues in citrus fruits
      Journal of Planar Chromatography, 6: 326-327 (1993)

    • Rossini C, Dellacassa E, Moyna P,
      Comparative study of the leaf oils of Psidium incanum and P. luridum
      J Essent Oil Res, 6: 513-515 (1994)

    • Sefafini L, Dillon AJP, Pistoriello YTM, Moyna P
      Effect of quinine sulphate on Saccharomyces cereviseae strains
      Acta Farmacéutica Bonaerense, 13: 67-70 (1994)

    • Ferreira F, Vázquez A, Moyna P, Kenne L
      Foliumin, a spirosten lactone saponin from Solanum amygdalifolium
      Phytochemistry, 36: 1473-1478 (1994)

    • Dellacassa E, Mahler G, Szedzki D, Moyna P, Alonso Paz E
      New chemotypes of Origanum X Applii (Domin) Boros from Uruguay
      J Essent Oil Res, 6: 389-393 (1994)

    • Rossini C, Pandolfi E, Dellacassa E, Moyna P
      Determination of 1,8-cineol in Eucalyptus essential oils by TLC- densitometry
      JAOAC (Int.), 78(1): 115-117 (1995)

    • Rossini C, Menéndez P, Dellacassa E, Moyna P
      Essential oils from leaves of Schinus molle and S. lentescifolius
      J Essent Oil Res (1995)

    • Ckless K, Schlottfeldt JL, Pasqual M, Moyna P, Henriques JA, Wajner M
      Inhibition of in vitro lymphocyte transformation by the isoquinoline alkaloid berberine
      J Pharm Pharmacol, 47(12A): 1029-1031 (1995)

    • Alonso Paz E, Cerdeiras MP, Fernández J, Ferreira F, Moyna P, Soubes M, Vázquez A, Vero S, Zunino L
      Screening of Uruguayan medicinal plants for antimicrobial activity
      J Ethnopharmacol, 45(1): 67-70 (1995)

    • Davyt D, Pandolfi E, Troche, Lilián; Heinzen H, Moyna P
      TLC-scanning of wheat seed waxes.
      Ann Asoc Química Argentina, 83: 1-5 (1995)

    • García S, Heinzen H, Hubbuch, Charles H, Martínez R, Devries JX, Moyna P
      Triterpene methyl ethers from Palmae epicuticular waxes
      Phytochemistry, 39: 1381-1382 (1995)

    • Dellacassa E, Rossini C, Lorenzo D, Moyna P, Verzera A, Trozzi A, Dugo G
      Uruguayan essential oils. Part III. Composition of the volatile fraction of lemmon essential oils
      J Essent Oil Res, 7: 25-37 (1995)

    • Heinzen H, Rodríguez S, Moyna P
      A simple experiment of phase transitions of lipid bilayers
      ALDEQ, 95-96: 18-24 (1996)

    • Heinzen H, De Vries J, Moyna P, Rember G, Martínez R, Tietze Lutz F
      Mass spectrometry of labelled triterpenoids
      Phytochem Anal, 7: 237-244 (1996)

    • Cesio V, Heinzen H, Servetto C, Torres M, Moyna P
      Rapid determination of lactose intolerance
      Química Analítica, 15: 140-143 (1996)

    • Olano I, Paz EA, Cerdeiras MP, Fernández J, Ferreira F, Moyna P, Soubes M, Vázquez A, Vero S, Bassagoda MJ
      Screening of Uruguayan medicinal plants for antimicrobial activity. Part II.
      J Ethnopharmacol, 53: 111-115 (1996)

    • Ferreira F, Soulé S, Vázquez A, Moyna P, Kenne L
      Steroid saponins from Solanum laxum
      Phytochemistry, 42: 1409-1416 (1996)

    • García S, García C, Heinzen H, Moyna P
      Chemical basis of the resistance of barley seeds to pathogenic fungi
      Phytochemistry, 44: 415-418 (1997)

    • Rodríguez S, Garda H, Heinzen H, Moyna P
      Effect of plant monofunctional triterpenes on dynamic and structural properties of dppc bilayers
      Chem Phys Lipids, 89: 119-130 (1997)

    • Güntner C, González A, Dos Reis R, González G, Vázquez A, Moyna P
      Effect of Solanum glycoalkaloids on the potato aphid
      J Chem Ecol, 23: 1651-1659 (1997)

    • Vázquez A, González G, Ferreira F, Moyna P, Kenne L
      Glycoalkaloids of Solanum comersonii
      Euphytica, 95: 195-201 (1997)

    • Ferreira F, Vázquez A, Güntner C, Moyna P
      Inhibition of the passive diffusion of cholic acid by the Ilex paragnariensis St. Hill. saponins
      Phytotherapy Res, 11: 79-81 (1997)

    • Soulé S, Vázquez A, González G, Moyna P, Ferreira F
      Preparative insolation of steroidal glycoalkaloids from Solanum tuberosum by MPLA
      Potato Res, 40: 413-416 (1997)

    • Dellacassa E, Rossini C, Lorenzo D, Moyna P, Verzera A, Cavazza Trozzi A, Dugo G
      Uruguayan essential oils. Part IV. Composition of lemon oil
      Flav Fragr J, 12: 247-255 (1997)

    • Dellacassa E, Lorenzo D, Verzera A, Cavazza A, Dugo G, Moyna P
      Uruguayan essential oils. Part V. Composition of Bergamot oil
      J Essent Oil Res, 9: 419-26 (1997)

    • García C, García S, Heinzen H, Moyna P, Niemeyer H
      Efficient method for quantification of hydroxamic acids by TLC-densitometry
      Phytochem Anal, 9: 278-282 (1998)

    • Dellacassa E, Lorenzo D, Moyna P, Frizzo C, Atti Serafini L, Dugo P
      Rosmarinus officinals essential oil from South of Brazil and Uruguay
      J Essent Oil Res, 11: 27-30 (1999)

    • Russi S, Pardo H, Heinzen H, Dias E, Moyna P, Mariezcurrena RA, Suescun L, Mombru AW
      1,4,4-trimethyl-9-phenyl-8-oxa-9-aza-bicyclo
      Acta Crystallogr C, 56(pt 6): 672-3 (2000)

    • Lorenzo D, Atti-Serafini L, Santos AC, Frizzo CD, Paroul N, Paz D, Dellacassa E, Moyna P
      Achyrocline satureioides essential oils from southern Brazil and Uruguay
      Planta Med, 66(5): 476-477 (2000)

    • Soulé S, Guntner C, Vázquez A, Argandona V, Moyna P, Ferreira F
      An aphid repellent glycoside from Solanum laxum
      Phytochemistry, 55: 217-222 (2000)

    • Cerdeiras MP, Fernández J, Soubes M, Vero S, Ferreira F, Moyna P, Olano I, Vázquez A
      A new antibacterial compound from Ibicella lutea
      J Ethnopharmacol, 73: 521-525 (2000)

    • Menéndez P, Rossini C, O'Neill S, Soubes M, Heinzen H, Moyna P
      Biotransformation of R-(+)-limonene by Pseudomonas putida and Streptococcus faecalis
      An Asoc Quím Arg, 88: 79-82 (2000)

    • Rech J, Frizzo CD, Atti Serafini L, Moyna P, Lorenzo D, Dellacassa E
      Composición química del aceite esencial de Menta (Italo Mitcham) cultivada en el sur de Brasil y en Uruguay
      Horticultura Brasileira, 18: 1008-1009 (2000)

    • Lorenzo D, Dellacassa E, Atti-Serafini L, Santos AC, Frizzo C, Paroul N, Moyna P, Mondello L, Dugo G
      Composition and stereoanalysis of Cymbopogon winterianus Jowitt oil from Southern Brazil
      Flavour Fragr J, 15(3): 177-181 (2000)

    • Rodríguez S, Cesio MV, Heinzen H, Moyna P
      Determination of the phospholipid/lipophilic compounds ratio in liposomes by thin-layer chromatography scanning densitometry
      Lipids, 35: 1033-1036 (2000)

    • Frizzo CD, Santos AC, Paroul N, Atti-Serafini L, Dellacassa E, Lorenzo D, Moyna P
      Essential oils of camphor tree (Cinnamomum camphora Nees Eberm.) cultivated in Southern Brazil
      Braz Arch Biol Technol, 43: 313-316 (2000)

    • Lorenzo D, Loayza I, Leigue L, Frizzo C, Dellacass E, Moyna P
      Asaricin, the main component of Ocotea opifera Mart. essential oil
      Nat Prod Lett, 15: 163-170 (2001)

    • Ren H, Grady S, Gamenara D, Heinzen H, Moyna P, Croft SL, Kendrick H, Yardley V, Moyna G
      Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds
      Bioorg Med Chem Lett, 11: 1851-1854 (2001)

    • Frizzo CD, Atti-Serafini LA, Dellacassa E, Lorenzo D, Moyna P
      Essential oil of Baccharis uncinella DC from Southern Brazil
      Flavour Fragr J, 16(4): 286-288 (2001)

    • Garcia C, Moyna P, Fernandez G et al.
      Allelopathic activity of Ammi majus L. fruit waxes
      Chemoecology, 12(2): 107-111 (2002)

    • Menendez P, Garcia C, Rodriguez P et al.
      Enzymatic systems involved in D-limonene biooxidation
      Braz Arch Biol Techn, 45(2): 111-114 (2002)

    • Russi S, Mombru AW, Gamenara D et al.
      4,5,6,9-tetramethoxy-11-phenyl-10-oxa-11-azatri-cyclo[7.2.2.0(2,7)]trideca-2 (7),3,5,12-tetraen-8-one
      Acta Crystallogr E, 57: O444-O446 Part 5 (2001)

    • Moyna P, Heinzen H
      Improving self-defense in plants. Martial arts for vegetables
      Pure Appl Chem, 73(8): 1325-1330 (2001)

    • Gamenara D, Dias E, Tancredi N et al.
      Hetero Diels-Alder adduct formation between nitrosobenzene and tetra-methyl purpurogallin and its retro-Diels-Alder reaction
      J Brazil Chem Soc, 12(4): 489-492 (2001)

    • Paroul N, Rota L, Frizzo C, Atti dos Santos AC, Moyna P, Escalona Gower A, Atti Serafíni L, Cassel E
      Chemical composition of the volatiles of Angelica root obtained by hydrodistillation and supercritical CO2 extraction
      J Essent Oil Res, 14: 282-285 (2002)

    • Francischetti EL, Vanderlinde R, Carrau JL, Moyna P
      Ethyl carbamate content in wines produced and commercialized in Southern Brazil
      Acta Farm Bonaerense, 21: 201-204 (2002)