La Q.F. Margot Paulino es investigadora Grado 5 en el Area Química del PEDECIBA. Ingresó al Programa en 1991. Desempeña sus actividades en la Cátedra de Química Cuántica, Facultad de Química.

Sus líneas de investigación son :

Dirección postal:
Cátedra de Química Cuántica,
Facultad de Química
Universidad de la República
Av. Gral. Flores 2124
Montevideo 11800
Uruguay
tel: (+598 2) 924 1908
fax: (+598 2) 924 1906
e-mail :margot@fq.edu.uy

Publicaciones

• 
  Paulino M, Stoppani A, Dubin M, Fernández S
  Inhibition of microsomal lipid peroxidation and cytochrome P-450 catalyzed reactions by nitrofuran compounds
  Free Rad Res Comm, 14 (5-6): 419-431 (1991)
• 
  Paulino M, Hikichi N, Hansz M, Stamato G
  Electronic properties and free radical production by nitrofuran compounds
  Free Rad Res Comm, 16: 207 (1992)
• 
  Stamato G, Nilsson O, Paulino M
  A computer model-built structure of the T. congolense trypanothione reductase in complex with NADP
  Molecular Engineering, 1: 357-375 (1992)
• 
  Paulino M, Hansz M, Tapia O, Hikichi N,
  A molecular dynamics study of glutathione reductase
  J Mol Struc (Theochem) (1994)
• 
  Caracelli I, Stamato FM, Mester B, Paulino M, Cerecetto H
  A new analogue of Nifurtimox
  Acta Crystallogr C, 52: 1281-1282 (1996)
• 
  Esteves A, Joseph L, Paulino M, Ehrlich R.
  Remarks on the phylogeny and structure of fatty acid binding proteins from parasitic platyhelminths
  Int J Parasitol, 27: 1013-1023 (1997)
• 
  Roxstrom G, Velazquez I, Paulino M, Tapia O
  DNA structure and fluctuations sensed from a 1.1ns molecular dynamics trajectory of a fully charged Zif268-DNA complex in water
  J Biomol Struct Dyn, 16: 301-312 (1998)
• 
  Paulino M, Esteves A, Vega M, Tabares G, Ehrlich R, Tapia O
  Modelling a 3D structure for EgDf1 from Echinococcus granulosus: putative epitopes, phosphorylation motifs and ligand
  J Comput Aided Mol Des, 12: 351-360 (1998)
• 
  Cerecetto H, Di Maio R, Ibarruri G, Seoane G, Denicola A, Peluffo G, Quijano C, Paulino M
  Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives
  Farmaco, 53: 89-94 (1998)
• 
  Iribarne F, Paulino M, Aguilera S, Murphy M, Tapia O
  Docking and molecular dynamics studies at trypanothione reductase and glutathione reductase active sites
  J Mol Model (Online), 8: 173-183 (2000)
• 
  Cerecetto H, Di Maio R, Gonzalez M, Risso M, Sagrera G, Seoane G, Denicola A, Peluffo G, Quijano C, Stoppani AO, Paulino M, Olea-Azar C, Basombrio MA
  Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. structure-activity relationships
  Eur J Med Chem, 35: 343-350 (2000)