imagen animada PEDECIBA
Investigadores :

Página personal del Dr. Claudio Scazzocchio


http://www.rau.edu.uy/pedeciba/personas/scazzocc.htm

El Dr. Claudio Scazzocchio es investigador Grado 5 en el Area Biología e investigador Asociado al Area de Química. Ingresó al Programa en 1990. Desempeña sus actividades en la Universidad Paris XI, Orsay, Francia.

Dirección postal:
Dépt. Microbiologie
Université Parix XI
Orsay
Francia
e-mail: scazzocchio@igmors.u-psud.fr



Publicaciones


  • Kulmburg P, Prang Hathieu M, Sequeval D, Scazzocchio C
    Correct intron splicing generates a new type of a putative zinc-binding domain in a transcriptional activator of Aspergillus nidulans
    FEBS Lett, 280: 11-16 (1991)

  • Daboussi MJ, Langin T, Deschamps F, Brygoo Y, Scazzocchio C, Burger G
    Heterologous expression of Aspergillus nidulans regulatory gene nirA in Fusarium oxysporum
    Gene, 109: 155-160 (1991)

  • Suárez T, Oestreicher N, Peñalva MA, Scazzocchio C
    Molecular cloning of the uaY regulatory gene of Aspergillus nidulans reveals a favoured region for DNA insertions
    Mol Gen Genet, 230: 369-375 (1991)

  • Burger G, Strauss J, Scazzocchio C, Franz Lang B
    nirA, the pathway-specific regulatory gene of nitrate assimilation in Aspergillus nidulans, encodes a putative GAL4-type zinc finger protein and contains 4 introns in highly conserved regions
    Mol Cell Biol. 11: 5746-5755 (1991)

  • Suárez T, Oestreicher N, Kelly J, Ong G, Sankarsingh T, Scazzocchio C
    The uaY positive control gene of Aspergillus nidulans: fine structure, isolation of constitutive mutants and reversion patterns
    Mol Gen Genet, 230: 359-368 (1991)

  • Oestreicher N, Sealy-Lewis H, Scazzocchio C
    Characterization, cloning and integrative properties of the gene encoding urate oxidase in Aspergillus nidulans
    Gene, 132: 185-192 (1993)

  • Sophianopoulou V, Suárez T, Diallinas G, Scazzocchio C
    Operator derepressed mutations in the proline utilisation gene cluster of Aspergillus nidulans
    Mol Gen Genet, 236: 209-213 (1993)

  • Gorfinkiel L, Diallinas G, Scazzocchio C
    Sequence and regulation of the uapA gene encoding a uric acid-xanthine permease in the fungus Aspergillus nidulans
    J Biol Chem, 268: 23376-23381 (1993)

  • Oestreicher N, Scazzocchio C
    Sequence, regulation and mutational analysis of the gene encoding urate oxidase in Aspergillus nidulans
    J Biol Chem, 268: 23382-23389 (1993)

  • Cubero B, Scazzocchio C
    Two different, adjacent and divergent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline gene cluster of Aspergillus nidulans
    EMBO J, 13: 407-415 (1994)

  • Oestreicher N, Scazzocchio C
    A single aminoacid change in a pathway-specific transcription factor results in differing degrees of constitutivity, hyperinducibility and derepression of several structural genes
    J Mol Biol, 249: 693-699 (1995)

  • Glatigny A, Scazzocchio C
    Cloning and molecular characterisation of hxA, the gene coding for the xanthine dehydrogenase (purine hydroxylase I) of Aspergillus nidulans
    J Biol Chem, 270: 3534-3550 (1995)

  • Diallinas G, Gorfinkiel L, Arst Jr H, Herb, Cecchetto G, Scazzocchio C
    Genetic and molecular characterization of a gene encoding a wide specificity purine permease of Aspergillus nidulans reveals a novel family of trasporters conserved in prokaryotes and eukaryotes
    J Biol Chem, 270: 8610-8622 (1995)

  • Tazebay UH, Sophianopoulou V, Cubero B, Scazzocchio C, Diallinas G
    Post-transcriptional control and kinetic characterization of proline transport in germinating conidiospores of Aspergillus nidulans
    FEMS Microbiol Lett, 132(1-2): 27-37 (1995)

  • Punt PJ, Strauss J, Smit R, Kinghorn JR, van den Hondel CA, Scazzocchio C
    The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NirA binding sites which act bidirectionally
    Mol Cell Biol, 15(10): 5688-99 (1995)

  • Suárez T, Vieira de Queiroz M, Estreicher N, Scazzocchio C
    The sequence and binding specificity of UaY, the specific regulator of the purine degradation pathway of Aspergillus nidulans suggest an evolutionary relationship with the PPR1 protein of Saccharomyces cerevisiae
    EMBO J, 14: 1453-1467 (1995)

  • González R, Scazzocchio C
    A rapid method for chromatin structure analysis in the filamentous fungus Aspergillus nidulans
    Nucleic Acids Res, 25(19):3 955-6 (1997)

  • Adams B, Smith AT, Doyle WA, Bray RC, Ryan M, Harrison R, Wolstenholme AJ, Romao MJ, Huber R, Demais S, Scazzocchio C
    Expression of wild-type and mutated Drosophila melanogaster xanthine dehydrogenases in Aspergillus nidulans
    Biochem Soc Trans, 25(3): 520S (1997)

  • Oestreicher N, Scazzocchio C, Suárez T
    Mutations in a dispensable region of the UaY transcription factor of Aspergillus nidulans differentially affect the expression of structural genes
    Mol Microbiol, 24(6): 1189-99 (1997)

  • Ravagnani A, Gorfinkiel L, Langdon T, Diallinas G, Adjadj E, Demais S, Gorton D, Arst HN Jr, Scazzocchio C
    Subtle hydrophobic interactions between the seventh residue of the zinc finger loop and the first base of an HGATAR sequence determine promoter-specific recognition by the Aspergillus nidulans GATA factor AreA
    EMBO J, 16(13): 3974-86 (1997)

  • Glatigny A, Hof P, Romao MJ, Huber R, Scazzocchio C.
    Altered specificity mutations define residues essential for substrate positioning in xanthine dehydrogenase
    J Mol Biol, 278(2): 431-8 (1998)

  • Diallinas G, Valdez J, Sophianopoulou V, Rosa A, Scazzocchio C
    Chimeric purine transporters of Aspergillus nidulans define a domain critical for function and specificity conserved in bacterial, plant and metazoan homologues
    EMBO J, 17(14): 3827-37 (1998)

  • Wolschek MF, Narendja F, Karlseder J, Kubicek CP, Scazzocchio C, Strauss J
    In situ detection of protein-DNA interactions in filamentous fungi by in vivo footprinting
    Nucleic Acids Res, 26(16): 3862-4 (1998)

  • Cazelle B, Pokorska A, Hull E, Green PM, Stanway G, Scazzocchio C
    Sequence, exon-intron organization, transcription and mutational analysis of prnA, the gene encoding the transcriptional activator of the prn gene cluster in Aspergillus nidulans
    Mol Microbiol, 28(2): 355-70 (1998)

  • Strauss J, Muro-Pastor MI, Scazzocchio C
    The regulator of nitrate assimilation in ascomycetes is a dimer which binds a nonrepeated, asymmetrical sequence
    Mol Cell Biol, 18(3): 1339-48 (1998)

  • Dzikowska A, Swianiewicz M, Talarczyk A, Wisniewska M, Goras M, Scazzocchio C, Weglenski P
    Cloning, characterisation and regulation of the ornithine transaminase (otaA) gene of Aspergillus nidulans
    Curr Genet, 35(2): 118-26 (1999)

  • Muro-Pastor MI, González R, Strauss J, Narendja F, Scazzocchio C
    The GATA factor AreA is essential for chromatin remodelling in a eukaryotic bidirectional promoter
    EMBO J, 18(6): 1584-97 (1999)

  • Amrani L, Cecchetto G, Scazzocchio C, Glatigny A
    The hxB gene, necessary for the post-translational activation of purine hydroxylases in Aspergillus nidulans, is independently controlled by the purine utilization and the nicotinate utilization transcriptional activating systems
    Mol Microbiol, 31(4): 1065-73 (1999)

  • Amrani L, Primus J, Glatigny A, Arcangeli L, Scazzocchio C, Finnerty V
    Comparison of the sequences of the Aspergillus nidulans hxB and Drosophila melanogaster ma-l genes with nifS from Azotobacter vinelandii suggests a mechanism for the insertion of the terminal sulphur atom in the molybdopterin cofactor
    Mol Microbiol, 38(1): 114-25 (2000)

  • Ramón A, Muro-Pastor MI, Scazzocchio C, Gonzalez R
    Deletion of the unique gene encoding a typical histone H1 has no apparent phenotype in Aspergillus nidulans
    Mol Microbiol, 35(1): 223-33 (2000)

  • Cubero B, Gómez D, Scazzocchio C
    Metabolite repression and inducer exclusion in the proline utilization gene cluster of Aspergillus nidulans
    J Bacteriol, 182(1): 233-5 (2000)

  • Valdez-Taubas J, Diallinas G, Scazzocchio C, Rosa AL
    Protein expression and subcellular localization of the general purine transporter UapC from Aspergillus nidulans
    Fungal Genet Biol, 30(2): 105-13 (2000)

  • Pokorska A, Drevet C, Scazzocchio C
    The analysis of the transcriptional activator PrnA reveals a tripartite nuclear localisation sequence
    J Mol Biol, 298(4): 585-96 (2000)

  • Scazzocchio C
    The fungal GATA factors
    Curr Opin Microbiol, 3(2): 126-31 (2000)

  • Tavoularis S, Scazzocchio C, Sophianopoulou V
    Functional expression and cellular localization of a green fluorescent protein-tagged proline transporter in Aspergillus nidulans
    Fungal Genet Biol, 33(2): 115-25 (2001)

  • Li Destri Nicosia MG, Brocard-Masson C, Demais S, Hua Van A, Daboussi MJ, Scazzocchio C
    Heterologous transposition in Aspergillus nidulans
    Mol Microbiol, 39(5): 1330-44 (2001)

  • Ribard C, Scazzocchio C, Oestreicher N
    The oxpA5 mutation of Aspergillus nidulans is an allele of adB, the gene encoding adenylosuccinate synthetase

    Mol Genet Genomics, 266: 701-710 (2001)

  • Adams B, Lowe DJ, Smith AT, Scazzocchio C, Demais S, Bray RC
    Expression of Drosophila melanogaster xanthine dehydrogenase in Aspergillus nidulans and some properties of the recombinant enzyme
    Biochem J, 362(Pt 1): 223-229 (2002)

  • Gomez D, Cubero B, Cecchetto G, Scazzocchio C
    PrnA, a Zn2Cys6 activator with a unique DNA recognition mode, requires inducer for in vivo binding
    Mol Microbiol, 44: 585-597 (2002)